Jinghai Chen - Personal Profile
JinghaiChen PhD
Principal Investigator
Institute of Translational Medicine of Zhejiang University
The Second Affiliated Hospital of Zhejiang University
Education
09/2001-12/2006 PhD
Peking Union Medical College & Chinese Academy of Medical Science
09/1997-07/2001 BS
Zhejiang University
Academic Appointments
2015/03-
Principal Investigator
Institute of Translational Medicine, the Second Affiliated Hospital,Zhejiang University
2011/12~015/03
Instructor
Boston Children’s Hospital, Harvard Medical School
2010/02~2011/12
Postdoctoral Fellow
Boston Children’s Hospital, Harvard Medical School
2007/03~2010/02
Postdoctoral Fellow
Sanford Research, University of South Dakota
Research area
Cardiovascular diseases are the main cause of death worldwide. The adult heart is primarily composed of terminally differentiated cardiomyocytes that exit the cell cycle. Under disease stress, cardiomyocytes die and the survival cardiomyocytes compensatorilyturn into hypertrophic remodeling. Then heart gets decompensation, eventually leading to heart failure. The molecular mechanism that controls cardiac remodeling and regeneration during diseases are not fully understood. My researches have been focused on cardiovascular diseases from development, adult heart remodeling and cardiac regeneration. Especially, I would like, but not limited, to elucidate how noncoding RNA regulatescardiac hypertrophy and cardiac regeneration during the cardiovascular diseases.We use cardiac cell system, mouse genetic model and AAV system to study the cardiovascular diseases. We apply a variety of molecular, cellular, and genetic approaches.
