Xiao Xu Laboratory
Xiao Xu
Qiushi Distinguished Professor,
Attending surgeon, doctoral supervisor
Research interest: Transplant Oncology and Regenerative Medicine
Xiao Xu

Selected Publications

l  Hu X, Chen G, Huang Y, Chen R, Xu X*. Integrated Multiomics Reveals Silencing of has_circ_0006646 Promotes TRIM21-Mediated NCL Ubiquitination to Inhibit Hepatocellular Carcinoma Metastasis. Adv Sci (Weinh). 2024: e2306915.

l  Wang S, Wang R, Xu N, Lu D*, Xu X*. SULT2B1-CS-DOCK2 Axis Regulates Effector T Cell Exhaustion in Hepatocellular Carcinoma. Hepatology. 2023;78(4):1064-1078.

l  Wang K, Dong L, Lu Q, Zheng S, Xu X*. Incorporation of protein induced by vitamin K absence or antagonist-II into transplant criteria expands beneficiaries of liver transplantation for hepatocellular carcinoma: A multi-center retrospective cohort study in China. Int J Surg. 2023;109(12):4135–44.

l  Yu J, Ling S, Hong J, Zheng S, Xu X*. TP53/mTORC1-mediated bidirectional regulation of PD-L1 modulates immune evasion in hepatocellular carcinoma. J Immunother Cancer. 2023;11(11):e007479.

l  Qiu N, Zhang Z, Wei X, Liu Y*, Xu X*. Peritoneal Gene Transfection of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand for Tumor Surveillance and Prophylaxis. Nano Lett. 2023;23(17):7859-7868.

l  Wang S, Xu N, Wang J, Wei Q*, Xu X*. BMI1-induced CD127+KLRG1+ memory T cells enhance the efficacy of liver cancer immunotherapy. Cancer Lett. 2023;571:216336.

l  Lu D, Lin Z, Wang R, Zheng S, Xu X*. Multi-omics profiling reveals Chitinase-3-like protein 1 as a key mediator in the crosstalk between sarcopenia and liver cancer. Redox Biol. 2022;58:102538.

l  Ling S, Zhan Q, Jiang G, Shan Q, Xu X*. E2F7 promotes mammalian target of rapamycin inhibitor resistance in hepatocellular carcinoma after liver transplantation. 2022. Am J Transplant ;22(10):2323-2336.

l  Xu S, Ling S, Shan Q, Shen Y*, Xu X*. Self-Activated Cascade-Responsive Sorafenib and USP22 shRNA Co-Delivery System for Synergetic Hepatocellular Carcinoma Therapy. Adv Sci (Weinh). 2021;8(5):2003042.

l  Xiang X, Wang J, Lu D, Xu X*. Targeting tumor-associated macrophages to synergize tumor immunotherapy. Signal Transduct Target Ther. 2021;6(1):75.

l  Ling S, Shan Q, Zhan Q, Zheng S*, Xu X*. USP22 promotes hypoxia-induced hepatocellular carcinoma stemness by a HIF1α/USP22 positive feedback loop upon TP53 inactivation. Gut. 2020;69(7):1322-1334.

l  Zhang C, Chen K, Wei R, Zheng S, Xu X*. The circFASN/miR-33a pathway participates in tacrolimus-induced dysregulation of hepatic triglyceride homeostasis. Signal Transduct Target Ther. 2020;5(1):23.

l  Ye Q, Ling S, Zheng S*, Xu X*. Liquid biopsy in hepatocellular carcinoma: Circulating tumor cells and circulating tumor DNA. Mol. Cancer. 2019;18(1).

l  Xu X, Lu D, Ling Q, Wei X, Zheng S*. Liver transplantation for hepatocellular carcinoma beyond the Milan Criteria, Gut. 2016; 65(6):1035-41.


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