Yuhao Wang Laboratory
Yuhao Wang
Principle Investigator
Yuhao Wang

Selected Publications

1. Y. Wang*, M. Wang, J. Chen, Y. Li, Z. Kuang, C. Dende, P. Raj, G. Quinn, Z. Hu, T. Srinivasan, B. Hassell, K. A. Ruhn, C. L. Behrendt, T. Liang, X. Dou, Z. Song, L. V. Hooper*. The gut microbiota reprograms intestinal lipid metabolism through long noncoding RNA Snhg9. Science. 381, 851-857 (2023). *Corresponding author

2. Y. Wang, Z. Kuang, X. Yu, K. A. Ruhn, M. Kubo and L. V. Hooper. The intestinal microbiota regulates body composition through NFIL3 and the circadian clock. Science. 357, 912-916 (2017).

3. Y. Wang and L. V. Hooper. Immune control of the microbiota prevents obesity. Science. 365, 316-317 (2019).

4. X. Yu*, Y. Wang*, M. Deng, Y. Li, K. A. Ruhn, C. Zhang, L. V. Hooper. The basic leucine zipper transcription factor NFIL3 directs the development of a common innate lymphoid cell precursor. Elife. 3, e04406 (2014). *Contributed equally.

5. Z. Kuang, Y. Wang, Y. Li, C. Ye, K. A. Ruhn, C. L. Behrendt, E. N. Olson, L. V. Hooper. The intestinal microbiota programs diurnal rhythms in host metabolism through histone deacetylase 3. Science. 365, 1428-1434 (2019).

6. S. Bel, M. Pendse, Y. Wang, K. A. Ruhn, B. Hassell, T. Leal, S. E. Winter, and L. V. Hooper. Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine. Science. 357, 1047-1052 (2017).

 7. Z. Hu, C. Zhang, L. Sifuentes-Dominguez, C. M. Zarek, D. C. Propheter, Z. Kuang, Y. Wang, M. Pendse, K. A. Ruhn, B. Hassell, C. L. Behrendt, B. Zhang, P. Raj, T. A. Harris-Tryon, T. A. Reese, L. V. Hooper. Small proline-rich protein 2A is a gut bactericidal protein deployed during helminth infection. Science. 374, eabe6723 (2021).

8. S. Gattu, Y. Bang, M. Pendse, C. Dende, A. L. Chara, T. A. Harris, Y. Wang, K. A. Ruhn, Z. Kuang, S. Sockanathan, and L. V. Hooper. Epithelial retinoic acid receptor β regulates serum amyloid A expression and vitamin A-dependent intestinal immunity. PNAS. 116, 10911-10916 (2019).

 


Institute of Translational Medicine, Zhejiang University
Address: 268 Kaixuan Road, Shangcheng District, Hangzhou City, Zhejiang Province
Tel: 0571-86971812 / 0571-88981576

Wechat Public