2021年
1.Cui D, Qu R, Liu D, Xiong X, Liang T, Zhao Y*. The cross talk between p53 and mTOR pathways in response to physiological and genotoxic stresses. Frontiers in Cell and Developmental Biology. 2021 (IF= 7.219, JCR 1区)
2.Ma Y#, Cui D#, Wang L#, Wang Y, Yang F, Pan H, Gong L, Zhang M, Xiong X*, Zhao Y*. P90 RSK confers cancer cell survival by mediating CHK1 degradation in response to glucose stress. Cancer Science. 2021 Oct 20. doi: 10.1111/cas.15168. Online ahead of print (IF= 6.716, JCR 1区)
3.Fei X, Li Z, Yang D, Kong X, Lu X, Shen Y, Li X, Xie S, Wang J, Zhao Y, Sun Y, Zhang J, Ye Z, Wang J, Cai Z*. Neddylation of Coro1a determines the fate of multivesicular bodies and biogenesis of extracellular vesicles. Journal of Extracellular Vesicles. 2021 Oct;10(12):e12153 (IF= 25.843, JCR 1区)
4.Zhang F, Zhao Y*, Sun Y*. USP2 is a SKP2 deubiquitylase that stabilizes both SKP2 and its substrates. Journal of Biological Chemistry. 2021 Aug 20;101109. doi: 10.1016/j.jbc.2021.101109. Online ahead of print (IF= 5.157, JCR 2区)
5.Gong L#, Shu J#, Chen X, Pan H, Chen G, Bi Y, Cui D, Li X, Liu D, Wang L, Wang Y, Liu P, Xiong X*, Zhao Y*. DEPTOR inhibits lung tumorigenesis by inactivating the EGFR-mTOR signals. Cancer Letters. 2021 Jul 25; 519 (2021): 263-276 (IF= 8.679, JCR 1区)
6.Bi Y, Cui D, Xiong X, Zhao Y*. The characteristics and roles of β-TrCP1/2 in carcinogenesis. FEBS Journal. 2021 Jun;288(11):3351-3374 (IF= 5.542, JCR 1区)
7.Bi Y, Chen X, Wei B, Wang L, Gong L, Li H, Xiong X, Zhao Y*. DEPTOR stabilizes ErbB2 to promote the proliferation and survival of ErbB2-positive breast cancer cells. Theranostics. 2021 Apr 19;11(13):6355-6369 (IF= 11.629, JCR 1区)
8.Bi Y, Gong L, Liu P, Xiong X, Zhao Y*. Nuclear ErbB2 represses DEPTOR transcription to inhibit autophagy in breast cancer cells. Cell Death & Disease. 2021 Apr 14;12(4):397. (IF= 8.713, JCR 1区)
9.Klionsky D*, et al, Zhao Y, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 2021 Jan;17(1):1-382. (IF= 16.586, JCR 1区)
2020年
1.Cui D#, Dai X#, Gong L, Chen X, Wang L, Xiong X, Zhao Y*. DEPTOR is a direct p53 target that suppresses cell growth and chemosensitivity. Cell Death & Disease. 2020 Nov 12;11(11):976. (IF=8.713, JCR 1区)
2.Chen J#, Xuan Z#, Song W, Han W, Chen H, Du Y, Xie H, Zhao Y, Zheng S*, Song P*. EAG1 enhances hepatocellular carcinoma proliferation by modulating SKP2 and metastasis through pseudopod formation. Oncogene. 2020 Oct 24. doi: 10.1038/s41388-020-01522-6. Online ahead of print. (IF=9.867, JCR 1区)
3.Cheng J, Lin M, Chu M, Gong L, Bi Y, Zhao Y*. Emerging role of FBXO22 in carcinogenesis. Cell Death Discovery. 2020 Jul 27;6:66 (IF=5.302, JCR 2区)
4.Xiong X, Cui D, Bi Y, Sun Y*, Zhao Y*. Neddylation modification of ribosomal protein RPS27L or RPS27 by MDM2 or NEDP1 regulates cancer cell survival. FASEB Journal. 2020 Aug 11; 34(10):13419-13429 (IF= 5.955, JCR 2区)
5.Zhao Y*, Xiong X, Sun Y*. Cullin-RING Ligase 5: Functional characterization and its role in human cancers. Seminars in Cancer Biology. 2020 Dec;67(Pt 2):61-79 (IF=15.707, JCR 1区)
6.Shu J, Cui D, Ma Y, Xiong X, Sun Y, Zhao Y*. SCFβ-TrCP-mediated degradation of TOP2β promotes cancer cell survival in response to chemotherapeutic drugs targeting topoisomerase II. Oncogenesis. 2020 Feb 3;9(2):8. (IF= 8.069, JCR 1区)
7.Gong L, Cui D, Xiong X*, Zhao Y*. Targeting Cullin-RING Ubiquitin Ligases and the Applications in PROTACs. Advances in Experimental Medicine and Biology. 2020;1217:317-347. (IF= 3.049, JCR 3区)
8.Chen X#, Xiong X#, Cui D#, Yang F, Wei D, Li H, Shu J, Bi Y, Dai X, Gong L, Sun Y, Zhao Y*. DEPTOR is an in vivo tumor suppressor that inhibits prostate tumorigenesis via the inactivation of mTORC1/2 signals. Oncogene. 2020 Feb;39(7):1557-1571. (IF=9.867, JCR 1区)
9.Cui D, Dai X, Shu J, Ma Y, Wei D, Xiong X, Zhao Y*. The cross talk of two family members of β-TrCP in the regulation of cell autophagy and growth. Cell Death and Differentiation. 2020 Mar;27(3):1119-1133. (IF= 15.828, JCR 1区)
10.Cui D#, Xiong X#, Shu J, Dai X, Sun Y, Zhao Y*. FBXW7 Confers Radiation Survival by Targeting p53 for Degradation. Cell Reports. 2020 Jan 14;30(2):497-509.e4. (IF= 10.394, JCR 1区)
2019年
1.Ma Y#, Cui D#, Xiong X, Inuzuka H, Wei W, Sun Y, North BJ*, Zhao Y*. SCFβ-TrCP ubiquitinates CHK1 in an AMPK-dependent manner in response to glucose deprivation. Molecular Oncology. 2019 13(2):307-321. (IF= 7.405, JCR 1区)
2.Du Y#, Song W#, Chen J, Chen H, Xuan Z, Zhao L, Chen J, Jin C, Zhou M, Tuo B, Zhao Y, Zheng S, Song P*. The potassium channel KCa3.1 promotes cell proliferation by activating SKP2 and metastasis through the EMT pathway in hepatocellular carcinoma. International Journal of Cancer. 2019, 145(2):503-516. (IF=7.968, JCR 1区)
2018年
1.Xiong X#, Liu X#, Li H, He H, Sun Y*, Zhao Y*. Ribosomal protein S27-like regulates autophagy via the β-TrCP-DEPTOR-mTORC1 axis. Cell Death & Disease. 2018, 9(11):1131. (IF=8.713, JCR 1区)
2.Chen X, Cui D, Bi Y, Shu J, Xiong X, Zhao Y*. AKT inhibitor MK-2206 sensitizes breast cancer cells to MLN4924, a first-in-class NEDD8-activating enzyme (NAE) inhibitor. Cell Cycle. 2018, 17(16):2069-2079. (IF=4.534, JCR 2区)
3.Wang J#, Cui D#, Gu S, Chen X, Bi Y, Xiong X, Zhao Y*. Autophagy regulates apoptosis by targeting NOXA for degradation. BBA Molecular Cell Research. 2018, 1865(8):1105-1113. (IF= 6.121, JCR 2区)
4.魏文毅*、孙毅*、曹诚、常智杰、陈策实、陈佺、程金科、冯仁田、高大明、胡荣贵、贾立军、姜天霞、金建平、李汇华、李卫、刘翠华、刘萱、马蕾娜、缪时英、饶枫、商瑜、宋质银、万勇、王恒彬、王平、王占新、吴缅、吴乔、谢旗、谢松波、谢志平、徐平、许执恒、杨波、阳成伟、应美丹、张宏冰、张令强、赵永超、周军、朱军、王琳芳、张宏、王琛、邱小波*. 类泛素蛋白及其中文命名. 科学通报. 2018, 63(25):2564-2569.
5.Chen J, Song W, Du Y, Li Z, Xuan Z, Zhao L, Chen J, Zhao Y, Tuo B, Zheng S*, Song P*. Inhibition of KLHL21 prevents cholangiocarcinoma progression through regulating cell proliferation and motility, arresting cell cycle and reducing Erk activation. Biochemical and Biophysical Research Communications. 2018, 499(3):433-440. (IF=3.575, JCR 3区)
6.Gu S, Cui D, Chen X, Xiong X*, Zhao Y*. PROTACs: An emerging targeting technique for protein degradation in drug discovery. Bioessays. 2018, 40(4):e1700247. (IF=5.022, JCR 2区) (Highlight by Advanced Science News，入选Web of science高引论文)
7.Zhao Y*, Tan M, Liu X, Xiong X*, Sun Y*. Inactivation of ribosomal protein S27-like confers radiosensitivity via the Mdm2-p53 and Mdm2-MRN-ATM axes. Cell Death & Disease. 2018, 9(2):145. (IF=8.713, JCR 1区)
2017年
1.Xu J, Zhou W, Yang F, Chen G, Li H, Zhao Y, Liu P, Li H, Tan M, Xiong X, Sun Y*. The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor. Nature Communications. 2017, 8:14002. (IF= 15.805, JCR 1区)
2.Song P#, Du Y#, Song W, Chen H, Xuan Z, Zhao L, Chen J, Chen J, Guo D, Jin C, Zhao Y, Tuo B, Zheng S*. KCa3.1 as an Effective Target for Inhibition of Growth and Progression of Intrahepatic Cholangiocarcinoma. Journal of Cancer. 2017, 8(9):1568-1578. (IF=4.277, JCR 2区)
2016年
1.Cui D, Xiong X, Zhao Y*. Cullin-RING ligases in regulation of autophagy. Cell Division. 2016, 11:8. (IF=5.596, JCR 2区)
2.Zhou X#, Tan M#, Nyati M, Zhao Y, Wang G*, Sun Y*. Blockage of neddylation modification stimulates tumor sphere formation in vitro and stem cell differentiation and wound healing in vivo. Proceedings of the National Academy of Sciences of the United States of America. 2016, 113(21):E2935-44. (IF=12.291, JCR 1区)
3.Klionsky D*, et al, Zhao Y, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016, 12(1):1-222. (IF=16.586, JCR 1区)
2015年以前
1.Zhao Y, Morgan M, Sun Y*. Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapy. Antioxidants & Redox Signaling. 2014, 21(17):2383-400. (IF=8.883, JCR 1区)
2.Xiong X#, Zhao Y#, Tang F, Wei D, Wang X, Thomas D, Zheng P, Liu Y, Sun Y*. Ribosomal protein S27-like is a physiological regulator of p53 that suppresses genomic instability and tumorigenesis. eLife. 2014, 3:e02236. (Selected by Faculty of 1000 Cell Biology) (IF=9.056, JCR 1区)
3.Li H, Sun G, Zhao Y, Thomas D, Greenson J, Zalupski M, Ben-Josef E, Sun Y*. DEPTOR has growth suppression activity against pancreatic cancer cells. Oncotarget. 2014, 5(24):12811-9. (IF=5.312)
4.Zhou W, Xu J, Zhao Y, Sun Y*. SAG/RBX2 is a novel substrate of NEDD4-1 E3 ubiquitin ligase and mediates NEDD4-1 induced chemosensitization. Oncotarget. 2014, 5:6746-55. (IF=5.312)
5.Li H#, Tan M#, Jia L, Wei D, Zhao Y, Chen G, Zhao L, Thomas D, Bear D, Sun Y*. Inactivation of SAG/RBX2 E3 ubiquitin ligase suppresses KrasG12D-driven lung tumorigenesis. Journal of Clinical Investigation. 2014, 124: 835-46. (IF=16.792, JCR 1区)
6.Zhao Y, Sun Y*. The FBW7-KLF2 axis regulates endothelial functions. Cell Research. 2013, 23:741-3. (IF= 25.924, JCR 1区)
7.Zhao Y, Sun Y*. Cullin-RING Ligases as attractive anti-cancer targets. Current Pharmaceutical Design. 2013, 19:3215-25. (IF= 3.309, JCR 3区)
8.Yang D#, Zhao Y#, Liu J, Sun Y*, Jia L*. Protective autophagy induced by RBX1/ROC1 knockdown or CRL inactivation via modulating the DEPTOR-MTOR axis. Autophagy. 2012, 8: 1856-8. (IF= 16.586, JCR 1区)
9.Zhao Y, Xiong X, Jia L, Sun Y*. Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis. Cell Death & Disease. 2012, 3: e386. (IF= 8.713, JCR 1区)
10.Zhao Y, Sun Y*. CUL4B ubiquitin ligase in mouse development: a model for human X-linked mental retardation syndrome? Cell Research. 2012, 22:1224–6. (IF= 25.924, JCR 1区)
11.Zhao Y, Sun Y*. Targeting the mTOR-DEPTOR pathway by CRL E3 ubiquitin ligases: therapeutic application. Neoplasia. 2012, 14: 360-7. (IF=7.230, JCR 2区) (Cover story)
12.Yang D, Zhao Y, Li A, Wang S, Wang G*, Sun Y*. Smac-mimetic compound SM-164 induces radiosensitization in breast cancer cells through activation of caspases and induction of apoptosis. Breast Cancer Research and Treatment, 2012, 133:189-99. (IF= 4.872, JCR 2区)
13.Zhao Y, Xiong X, Sun Y*. DEPTOR, an mTOR inhibitor, is a physiological substrate of SCF(βTrCP) E3 ubiquitin ligase and regulates survival and autophagy. Molecular Cell. 2011, 44: 304-16. (IF= 19.639, JCR 1区) (Research Highlight by Nature Reviews Molecular Cell Biology)
14.Tan M#, Zhao Y#, Kim S, Liu M, Jia L, Saunders T, Zhu Y*, Sun Y*. SAG/RBX2/ROC2 E3 ubiquitin ligase is essential for vascular and neural development by targeting NF1 for degradation. Developmental Cell. 2011, 21: 1062-76. (IF= 12.332, JCR 1区)
15.Xiong X, Zhao Y, He HB, Sun Y*. Ribosomal protein S27-like and S27 interplay with p53-MDM2 axis as a target, a substrate and a regulator. Oncogene, 2011, 30: 1798–1811. (IF=9.867, JCR 1区)
16.Tan M, Zhu Y, Kovacev J, Zhao Y, Pan Z, Spitz, D, Sun Y*. Disruption of Sag/Rbx2/Roc2 induces radiosensitization by increasing ROS levels and blocking NF-κB activation in mouse embryonic stem cells. Free Radical Biology and Medicine, 2010, 49: 976-83. (IF= 7.934, JCR 1区)
17.Zhao Y#, Shao W#, Wei H, Qiao J, Lu Y, Sun Y, Mitchelson K, Cheng J, Zhou Y*. Development of a novel oligonucleotide array-based transcription factor assay platform for genome-wide active transcription factor profiling in Saccharomyces cerevisiae. Journal of Proteome Research. 2008, 7: 1315-25. (IF=4.466, JCR 1区) * co-first author
18.Yang Q#, Zhao Y#, Xiong Q, Cheng J*. Rapid chip-based capillary electrophoretic mobility shift assay with negative pressure injection for the binding study of transcription factor Abf1 in Saccharomyces cerevisiae. Electrophoresis. 2008, 29: 5003-9. (IF=3.535, JCR 2区) * co-first author
19.Qiao J, Shao W, Wei H, Sun Y, Zhao Y, Xing W, Zhang L, Mitchelson K, Cheng J*. Novel high-throughput profiling of human transcription factors and its use for systematic pathway mapping. Journal of Proteome Research, 2008, 7: 2769-79. (IF=4.466, JCR 1区)
20.Sun Y, Zhang Y, Zeng L, Wu J, Wei L, Ren A, Shao W, Qiao J, Zhao Y, Zhang L, Mitchelson K, Cheng J*. Broad profiling of DNA-binding transcription factor activities improves regulatory network construction in adult mouse tissues. Journal of Proteome Research, 2008, 7: 4455-64. (IF=4.466, JCR 1区)
21.Yin H, Zhao Y, Zhang Y, Zhang H, Xu L, Zou Z, Yang W, Cheng J, Zhou Y*. Genome-wide analysis of the expression profile of Saccharomyces cerevisiae in response to treatment with the plant isoflavone, wighteone, as a potential antifungal agent. Biotechnology Letters, 2006, 28:99-105. (IF= 2.461, JCR 3区)
22.Yin H, Xu H, Zhao Y, Yang W, Cheng J, Zhou Y*. Cyclooxygenase- independent effects of aspirin on HT-29 human colon cancer cells, revealed by oligonucleotide microarrays. Biotechnology Letters, 2006, 28:1263-70. (IF= 2.461, JCR 3区)
23.Shao W, Wei H, Qiao J, Zhao Y, Sun Y, Zhou Y, Cheng J*. Parallel profiling of active transcription factors using an oligonucleotide array-based transcription factor assay (OATFA). Journal of Proteome Research, 2005, 4:1451-6. (IF=4.466, JCR 1区)
