Corresponding author publications
1. Yang L#, Wang H#, Yang X#, Wu Q, An P, Jin X, Liu W, Huang X, Li Y, Yan S, Shen S, Liang T*, Min J*, Wang F*. Auranofin mitigates systemic iron overload and induces Auranofin mitigates systemic iron overload and induces ferroptosis via distinct mechanisms. Signal Transduction and Targeted Therapy. (Accepted 2020 June 19)
2. Yang X#, Wang H#, Xie E, Tang B, Mu Q, Song Z, Chen J, Wang F, Min J*. Rewiring ERBB3 and ERK signaling confers resistance to FGFR1 inhibition in gastrointestinal cancer harbored an ERBB3-E928G mutation. Protein&Cell. (Accepted 2020 June 15)
3. Yu Y#, Jiang L#, Wang H, Shen Z, Cheng Q, Zhang P, Wang J, Wu Q, Fang X, Duan L, Wang S, Wang K, An P, Shao T, Chung RT, Zheng S, Min J*, Wang F*. Hepatic transferrin plays a role in systemic iron homeostasis and liver ferroptosis. Blood. 2020 May 6
4. Fang X#, Cai Z, Wang H, Han D, Cheng Q, Zhang P, Gao F, Yu Y, Song Z, Wu Q, An P, Huang S, Pan J, Chen HZ, Chen J, Linkermann A, Min J*, Wang F*. Loss of cardiac ferritin H facilitates cardiomyopathy via Slc7a11-mediated ferroptosis. Circulation Research. 2020 Apr 30.
5. Li J#, Pan X#, Pan G, Song Z, He Y, Zhang S, Ye X, Yang X, Xie E, Wang X, Mai X, Yin X, Tang B, Shu X, Chen P, Dai X, Tian Y, Yao L, Han M, Xu G, Zhang H, Sun J, Chen H, Wang F*, Min J* and Xie L*. Transferrin receptor 1 regulates thermogenic capacity and cell fate in brown/beige adipocytes. Advanced Science. 2020 Mar 4.
6. An P #, Wang J#, Wang H, Jiang L, Wang J, Min J*, Wang F*. Gnpat does not play an essential role in systemic iron homeostasis in murine model. Journal of Cellular and Molecular Medicine. 2020 Feb 28.
7. Wang S#, He X#, Wu Q, Jiang L, Chen L, Yu Y, Zhang P, Huang X, Wang J, Ju Z, Min J *, Fudi Wang*. Transferrin Receptor 1-Mediated Iron Uptake Plays An Essential Role In Hematopoiesis. Haematologica. 2019 Oct 10.
8. Jiang L#, Wang K#, Lo K#, Zhong Y, Yang A, Fang X, Akezhuoli H, Song Z, Chen L, An P, Xu M*, Min J*, Wang F*. Sex-specific association of circulating ferritin level and risk of type 2 diabetes: A dose-response meta-analysis of prospective studies. The Journal of Clinical Endocrinology & Metabolism. 2019 Oct 1.
9. Wang X#, Wu W#, Zheng W, Fang X, Chen L, Rink L, Min J*, Wang F*. Zinc supplementation improves glycemic control for diabetes prevention and management: a systematic review and meta-analysis of randomized controlled trials. The American Journal of Clinical Nutrition. 2019 Jul 1.
10. Zhang P#, He J, Wang F, Gong J, Wang L, Wu Q, Li W, Liu H, Wang J, Zhang K, Li M, Huang X, Pu C, Li Y, Jiang F, Wang F *, Min J *, Chen X*. Hemojuvelin is a novel suppressor for Duchenne muscular dystrophy and age‐related muscle wasting. Journal of Cachexia, Sarcopenia and Muscle. 2019 Mar 18.
11. Li G #, Zhang Y#, Xie E, Yang X, Wang H, Wang X, Li W, Song Z, Mu Q, Zhan W, Wu Q, Huang J, Chen Y, Zhang Y, Wang F, Min J*. Functional characterization of a potent anti-tumor polysaccharide in a mouse model of gastric cancer. Life Sciences. 2019 Feb 15.
12. Fang X#, Wang H, Han D, Xie E, Yang X, Wei J, Gu S, Gao F, Zhu N, Yin X, Cheng Q, Zhang P, Dai W, Chen J, Yang F, Yang HT, Linkermann A*, Gu W*, Min J*, Wang F*. Ferroptosis as a target for protection against cardiomyopathy. Proceedings of the National Academy of Sciences. 2019 Feb 12.
13. Gao H#, Dai W, Zhao L*, Min J*, Wang F*. The Role of Zinc and Zinc Homeostasis in Macrophage Function. Journal of Immunology Research. 2018 Dec 6.
14. Wang X#, Gao H#, Wu W, Xie E, Yu Y, He X, Li J, Zheng W, Wang X, Cao X, Meng Z, Chen L*, Min J*, Wang F*. The zinc transporter Slc39a5 controls glucose sensing and insulin secretion in pancreatic β-cells via Sirt1- and Pgc-1α-mediated regulation of Glut2. Protein & Cell.2018 Oct 15.
15. Zeng Y*, Nie C, Min J*, Chen H, Liu X, Ye R, Chen Z, Bai C, Xie E, Yin Z, Lv Y, Lu J, Li J, Ni T, Bolund L, Land KC, Yashin A, O'Rand AM, Sun L, Yang Z, Tao W, Gurinovich A, Franceschi C, Xie J, Gu J, Hou Y, Liu X, Xu X, Robine JM, Deelen J, Sebastiani P, Slagboom E, Perls T, Hauser E, Gottschalk W, Tan Q, Christensen K, Shi X, Lutz M, Tian XL, Yang H, Vaupel J. Sex differences in genetic associations with longevity. JAMA Network Open. 2018 Aug 24.
16. Zhao X#, Liu X#, Zhang A#, Chen H#, Huo Q, Li W, Ye R, Chen Z, Liang L, Liu QA, Shen J, Jin X, Li W, Nygaard M, Liu X, Hou Y, Ni T, Bolund L, Gottschalk W, Tao W, Gu J, Tian XL, Yang H, Wang J, Xu X, Lutz MW, Min J*, Zeng Y*, Nie C*. The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese. Aging (Albany NY). 2018 Jun 5.
17. Yin X#, Wu Q#, Monga J, Xie E, Wang H, Wang S, Zhang H, Wang ZY, Zhou T, Shi Y, Rogers J, Lin H, Min J*, Wang F*. HDAC1 governs iron homeostasis independent of histone deacetylation in iron-overload murine models. Antioxidants & Redox Signaling. 2018 May 1.
18. Fang X#, Wei J#, He X#, Lian J#, Han D, An P, Zhou T, Liu S, Wang F*, Min J*. Quantitative association between body mass index and the risk of cancer: A global Meta-analysis of prospective cohort studies. International Journal of Cancer. 2018 Apr 26.
19. An P#, Wang H#, Wu Q, Wang J, Xia Z, He X, Wang X, Chen Y, Min J*, Wang F*. Smad7 deficiency decreases iron and haemoglobin through hepcidin up-regulation by multilayer compensatory mechanisms. Journal of Cellular and Molecular Medicine, 2018 Mar 30.
20. Zhang Y#, Wang X#, Wu Q, Wang H, Zhao L, Wang X, Mu M, Xie E, He X, Shao D, Shang Y, Lai Y, Ginzburg Y, Min J* and Wang F*. Adenine alleviates iron overload by cAMP/PKA mediated hepatic hepcidin in mice. Journal of Cellular Physiology, 2018 Mar 30.
21. Gao H, Zhao L, Wang H, Xie E, Wang X, Wu Q, Yu Y, He X, Ji H, Rink L, Min J, Wang F. Metal transporter Slc39a10 regulates susceptibility to inflammatory stimuli by controlling macrophage survival. Proceedings of the National Academy of Sciences. 2017 Dec 5;114(49):12940-12945. Epub 2017 Nov 2
22. Wang H, An P, Xie E, Wu Q, Fang X, Gao H, Zhang Z, Li Y, Wang X, Zhang J, Li G, Yang L, Liu W, Min J*, Wang F*. Characterization of Ferroptosis in Murine Models of Hemochromatosis. Hepatology. 2017 Aug;66(2):449-465. Epub 2017 May 162017.
23. Yin X, Wu Q, Monga J, Xie E, Wang H, Wang S, Zhang H, Wang ZY, Zhou T, Shi Y, Rogers J, Lin H, Min J*, Wang F*. HDAC1 Governs Iron Homeostasis Independent of Histone Deacetylation in Iron-overload Murine Models. Antioxidants & Redox Signaling. 2017 Nov 7.
24. Wu Q, Shen Y, Tao Y, Wei J, Wang H, An P, Zhang Z, Gao H, Zhou T, Wang F*, Min J*. Hemojuvelin regulates the innate immune response to peritoneal bacterial infection in mice. Cell Discovery. 2017 Aug 15; 3:17028. doi: 10.1038/celldisc.2017.28.
25. Xia Z, Wei J, Li Y, Wang J, Li W, Wang K, Hong X, Zhao L, Chen C, Min J*, Wang F*. Zebrafish slc30a10 deficiency revealed a novel compensatory mechanism of Atp2c1 in maintaining manganese homeostasis. PLOS Genetics. 2017 Jul 10;13(7): e1006892.doi: 10.1371/journal.pgen.1006892.
26. Wang X#, An P#, Zeng J, Liu X, Wang B, Fang X, Wang F*, Ren G*, Min J*. Serum ferritin in combination with prostate-specific antigen improves predictive accuracy for prostate cancer. Oncotarget 2017. doi:10.18632/oncotarget.14977
27. Fang X, Wei J, He X, An P, Wang H, Jiang L, Shao D, Liang H, Li Y, Wang F*, Min J*. Landscape of dietary factors associated with risk of gastric cancer: A systematic review and dose-response meta-analysis of prospective cohort studies. European Journal of Cancer. 2015; 51:2820–2832.
28. An P, Wang H, Wu Q, Guo X, Wu A, Zhang Z, Zhang D, Xu X, Mao Q, Shen X, Zhang L, Xiong Z, He L, Liu Y, Min J*, Zhou D*, Wang F*. Elevated serum transaminase activities were associated with increased serum levels of iron regulatory hormone hepcidin and hyperferritinemia risk. Scientific Reports. 2015; 5:13106.
29. Wu Q, Wang H, An P, Tao Y, Deng J, Zhang Z, Shen Y, Min J*, Wang F*. HJV and HFE Play Distinct Roles in Regulating Hepcidin. Antioxidants & Redox Signaling. 2015;22(15):1325-36.
First Author publications
1.Min J, Fedele G, Zaslavsky A, Reczek E, Guney I, Strochlic D, Bronson RT, Hahn WC, Ryeom S, Loda M and Cichowski K. (2010) An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and NF-kB. Nature Medicine, Mar;16(3):286-94 (Article)
2.Min J, Mesika A, Sivaguru M, Van Veldhoven PP, Alexander H, Anthony H. Futerman AH and Alexander S. (2007) LASS1 dihydroceramide synthase induced sensitivity to cisplatin is mediated through the activation of p38 MAP kinase and is abrogated by sphingosine kinase 1. Molecular Cancer Research. 5(8):801-12 (Cover article)
3.Min J., Sridetive P., Hanigan MH., Alexander H. (2006) Sensitive cell viability assay for use in drug screens and for studying the mechanism of action of drugs in Dictyosteliumdiscoideum. Biotechniques, 41(5):591-5. (Featured article)
4.Min J., Van Veldhoven PP, Zhang L, Hanigan MH, Alexander H, Alexander S. (2005) Sphingosine-1-Phosphate Lyase Regulates Sensitivity of Human Cells to Select Chemotherapy Drugs in a p38-Dependent Manner. Molecular Cancer Research,3:287-296.
5.Min J., Traynor D., Stegner A.L, Zhang L., Hanigan M.H., Alexander H., and Alexander S. (2005) Sphingosine kinase regulates the sensitivity of Dictyostelium Discoideum cells to the anticancer drug cisplatin. Eukaryotic Cell, 4:178-189
6.Min J, Stegner A.L, Alexander H. and Alexander S. (2004) Overexpression of sphingosine-1-phosphate lyase or inhibition of sphingosine kinase in Dictyostelium discoideum results in a selective increase in sensitivity to platinum based chemotherapy drugs. Eukaryotic Cell, 3:795-805
7.Jaeger S#, Min J#, Nigsch F, Camargo M, Hutz J, Cornett A, Cleaver S, Buckler A, Jenkins J. L. Causal Network Models for Predicting Compound Targets and Driving Pathways in Cancer. Journal of Biomolecular Screening. 2014;19(5):791-802.
8.Zeng Y#, Nie C#, Min J#, Liu X#, Li M, Chen H, Xu H, Wang M, Ni T, Li Y, Yan H, Zhang JP, Song C, Chi LQ, Wang HM, Dong J, Zheng GY, Lin L, Qian F, Qi Y, Liu X, Cao H, Wang Y, Zhang L, Li Z, Zhou Y, Wang Y, Lu J, Li J, Qi M, Bolund L, Yashin A, Land KC, Gregory S, Yang Z, Gottschalk W, Tao W, Wang J, Wang J, Xu X, Bae H, Nygaard M, Christiansen L, Christensen K, Franceschi C, Lutz MW, Gu J, Tan Q, Perls T, Sebastiani P, Deelen J, Slagboom E, Hauser E, Xu H, Tian XL, Yang H, Vaupel JW. Novel loci and pathways significantly associated with longevity. Scientific Reports 2016; 6:21243.
Co-Author publications
1.Joris Deelen#*, Daniel S. Evans#*, Dan E. Arking, Niccolò Tesi, Marianne Nygaard, Xiaomin Liu, Mary K. Wojczynski, Mary L. Biggs, Ashley van der Spek, Gil Atzmon, Erin B. Ware, Chloé Sarnowski, Albert V. Smith, Ilkka Seppälä, Heather J. Cordell, Janina Dose, Najaf Amin, Alice M. Arnold, Kristin L. Ayers, Nir Barzilai, Elizabeth J. Becker, Marian Beekman, Hélène Blanché, Kaare Christensen, Lene Christiansen, Joanna C. Collerton, Sarah Cubaynes, Steven R. Cummings, Karen Davies, Birgit Debrabant, Jean-François Deleuze, Rachel Duncan, Jessica D. Faul, Claudio Franceschi, Pilar Galan, Vilmundur Gudnason, Tamara B. Harris, Martijn Huisman, Mikko A. Hurme, Carol Jagger, Iris Jansen, Marja Jylhä, Mika Kähönen, David Karasik, Sharon L. R. Kardia, Andrew Kingston, Thomas B. L. Kirkwood, Lenore J. Launer, Terho Lehtimäki, Wolfgang Lieb, Leo-Pekka Lyytikäinen, Carmen Martin-Ruiz, Junxia Min, Almut Nebel, Anne B. Newman, Chao Nie, Ellen A. Nohr, Eric S. Orwoll, Thomas T. Perls, Michael A. Province, Bruce M. Psaty, Olli T. Raitakari,59,60 Marcel J. T. Reinders,7 Jean-Marie Robine, Jerome I. Rotter, Paola Sebastiani,18 Jennifer Smith, Thorkild I. A. Sørensen, Kent D. Taylor, André G. Uitterlinden, Wiesje van der Flier, Sven J. van der Lee, Cornelia M. van Duijn, Diana van Heemst, James W. Vaupel, David Weir, Kenny Ye, Yi Zeng, Wanlin Zheng, Henne Holstege, Douglas P. Kiel, Kathryn L. Lunetta, P. Eline Slagboom#*, and Joanne M. Murabito #*. A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nature Communications. 2019 Aug 14.
2.Fang Xuexian, Min Junxia, Wang Fudi*. A dose-response association between serum ferritin and metabolic syndrome? Atherosclerosis, 2018 Oct 21.
3.Jifei Ma#, Qianwen Li#, Xuexian Fang, Liyun Chen, Yuzhen Qiang, Jianyao Wang, Qingqing Wang, Junxia Min, Shenshen Zhang*, Fudi Wang*. Increased total iron and zinc intake and lower heme iron intake reduce the risk of esophageal cancer: A dose-response meta-analysis. Nutrition Research. 2018 Aug 3.
4.Fang X, Han D, Cheng Q, Zhang P, Zhao C, Min J, Wang F*. Association of Levels of Physical Activity With Risk of Parkinson Disease: A Systematic Review and Meta-analysis. JAMA Network Open. 2018 Sep 7.
5.Xin Y, Gao H, Wang J, Qiang Y, Imam MU, Li Y, Wang J, Zhang R, Zhang H, Yu Y, Wang H, Luo H, Shi C, Xu Y, Hojyo S, Fukada T, Min J, Wang F*. Manganese transporter Slc39a14 deficiency revealed its key role in maintaining manganese homeostasis in mice. Cell Discovery. 2017 Jul 18; 3:17025. doi: 10.1038/celldisc.2017.25.
6.Zhao L, Lian J, Tian J, Shen Y, Ping Z, Fang X, Min J, Wang F*. Dietary intake of heme iron and body iron status are associated with the risk of gestational diabetes mellitus: a systematic review and meta-analysis. Asia Pac J Clin Nutr. 2017;26(6):1092-1106. doi: 10.6133/apjcn.022017.09.
7.An P, Jiang L, Guan Y, Wang H, Wang J, Tian Y, Yang W, Shi Y, Xue J, Min J, Wang F*. Identification of hereditary hemochromatosis pedigrees and a novel SLC40A1 mutation in Chinese population. Blood Cells, Molecules, and Diseases. 2017, 63:34-36.
8.Fang X, Wang K, Han D, He X, Wei J, Zhao L, Imam MU, Ping Z, Li Y, Xu Y, Min J, Wang F*. Dietary magnesium intake and the risk of cardiovascular disease, type 2 diabetes, and all-cause mortality: a dose–response meta-analysis of prospective cohort studies. BMC Medicine 2016, 14, 210.
9.Zeng Y, Chen H, Ni T, Ruan R, Nie C, Liu X, Feng L, Zhang F, Lu J, Li J, Li Y, Tao W, Gregory SG, Gottschalk W, Lutz MW, Land KC, Yashin A, Tan Q, Yang Z, Bolund L, Ming Q, Yang H, Min J, Willcox DC, Willcox BJ, Gu J, Hauser E, Tian XL, Vaupel JW. Interaction Between the FOXO1A-209 Genotype and Tea Drinking Is Significantly Associated with Reduced Mortality at Advanced Ages. Rejuvenation Research. 2016; 19(3):195-203.
10.Fang X, Wang H, An P, Min J, and Wang F*. Cardiomyocyte-specific deletion of ferroportin using MCK-Cre has no apparent effect on either cardiac iron homeostasis. International Journal of Cardiology, 2015 Dec 15;201:90-2.
11.Mu M, An P, Shen X, Wu Qian, Shao D, Wang H, Zhang Y, Zhang S, Yao H, Min J, Wang F*. The dietary flavonoid myricetin regulates iron homeostasis by suppressing hepcidin expression. Journal of Nutritional Biochemistry. 2015;10.015.
12.Zhou Q., Derti A., Ruddy D., Rakiec D., Kao I., Lira M, Gibaja V, Chan H, Yang Y, Min J, Schlabach M, Stegmeier F. A chemical genetics approach for the functional assessment of novel cancer genes. Cancer Research. 2015 May 15;75(10):1949-58.
13.Fang X, An P, Wang H, Wang X, Shen X, Li X, Min J, Liu S and Wang F. Dietary intake of heme iron and risk of cardiovascular disease: a dose-response meta-analysis of prospective cohort studies. Nutr Metab Cardiovasc Dis, 2015; 25(1): 24-35.
14.Huang T#, Lan L#, Fang X, An P, Min J, Wang F*. Promises and Challenges of Big Data Computing in Health Sciences. Big Data Research, 2015, 2–11.
15.Wang Y, Lee YM, Baitsch L, Huang A, Xiang Y, Tong H, Lako A, Von T, Choi C, Lim E, Min J, Li L, Stegmeier F, Schlegel R, Eck MJ, Gray NS, Mitchison TJ, Zhao J. MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells. eLife.2014; e01763.
16.Sridevi P, Alexander H, Laviad EL, Min J, Mesika A, Hannink M, Futerman AH, Alexander S. (2010) Stress-induced ER to Golgi translocation of ceramide synthase 1 is dependent on proteasomal processing. Exp Cell Res. 316(1):78-91.
17.Driessche NV, Alexander H, Min J, Kuspa A, Alexander S and Shaulsky G. (2007) Global Transcriptional Responses to Cisplatin in Dictyostelium discoideum Identify Potential Drug Targets. PNAS, 104(39):15406-11
