Linyu Lu Laboratory
Linyu Lu
Professor, Doctoral Supervisor
Research Interests:
DNA damage repair in spermatogenesis and tumorigenesis.
Linyu Lu

Selected Publications

Xie C, Wang W, Tu C, Meng L, Lu G, Lin G, Lu LY, Tan YQ*. (2022) Meiotic recombination: insights into its mechanisms and its role in human reproduction with a special focus on non-obstructive azoospermia. Human Reproduction Update, Online ahead of print. 

Li L, Tan YQ, Lu LY*. (2022) Defective piRNA Processing and Azoospermia. New England Journal of Medicine, 386:1675-1676. 

Liu Y*, Lu LY*. (2021) BRCA1: a key player at multiple stages of homologous recombination in DNA double-strand break repair. Genome Instability & Disease, 2:164–174. (Invited review) 

Liu K#, Wang Y#, Zhu Q, Li P, Chen J, Tang Z, Shen Y, Cheng X, Lu LY*, Liu Y*. (2020) Aberrantly expressed HORMAD1 disrupts nuclear localization of MCM8-MCM9 complex and compromises DNA mismatch repair in cancer cells. Cell Death & Disease, 11:519. 

Liu Y*, Lu LY*. (2020) BRCA1 and homologous recombination: implications from mouse embryonic development. Cell & Bioscience, 10,49. (Invited review)

Chen J#, Li P#, Song L, Bai L, Huen MS, Liu Y*, Lu LY*. (2020) 53BP1 loss rescues embryonic lethality but not genomic instability of BRCA1 total knockout mice. Cell Death & Differentiation, 27:2552–2567. 

Zhang B, Tang Z, Li L, Lu LY*. (2020) NBS1 is required for SPO11-linked DNA double-strand break repair in male meiosis. Cell Death & Differentiation, 27:2176–2190.

Institute of Translational Medicine, Zhejiang University
Address: 268 Kaixuan Road, Shangcheng District, Hangzhou City, Zhejiang Province
Tel: 0571-86971812 / 0571-88981576

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