XiangJun Chen Laboratory
XiangJun Chen
Researcher, Doctoral Supervisor
Research Interests:
Studying the pathogenesis of cataracts and exploring
the prevention and treatment strategies and so on
XiangJun Chen

Selected Publications

1, Chen, X.J. *, Zhang, X.H. *, Hu, L.D., Yang, Y., and Yan, Y.B. (2016). DsCaf1 is involved in environmental stress response of Dunaliella salina. Int J Biol Macromol. 82, 369-374.  

2, Wang, T. *, Chen, X.J. *, Han, J., Ma, S., Liu, Z., and Yang, Y. (2016). Effects of the cofactor binding sites on the activities of secondary alcohol dehydrogenase (SADH). Int J Biol Macromol.88, 385-391.  

3, Liu, H. *, Gao, Y.S. *, Chen, X.J., Zhou, H.M., Yan, Y.B., and Gong, H. (2016). A single residue substitution accounts for the significant difference in thermostability between two isoforms of human cytosolic creatine kinase. Sci Rep. 6, 21191

4, Zhao, L. *, Chen, X.J. *, Zhu, J. *, Xi, Y.B. *, Yang, X. *, Hu, L.D. *, et al. 2015. Lanosterol reverses protein aggregation in cataracts. Nature. 523(7562): 607-11.  

5, Xi, Y.B. *, Chen, X.J. *, Zhao, W.J. *, and Yan, Y.B. 2015. Congenital cataract-causing mutation G129C in gammaC-crystallin promotes the accumulation of two distinct unfolding intermediates that form highly toxic aggregates. J Mol Biol. 427(17): 2765-81.

6, Chen, X.J. *, Wu, M.J. *, and Yan, Y.B. 2015. Dunaliella salina Hsp90 is halotolerant. Int J Biol Macromol. 75: 418-425.  

7, Li, X.H., Chen, X.J., Ou, W.B., Zhang, Q., et al. 2013. Knockdown of creatine kinase B inhibits ovarian cancer progression by decreasing glycolysis. Int J Biochem Cell Biol. 45(5): 979-986.

8, Chen, Z. *, Chen, X.J. *, Xia, M.D. *, He, H.W. *, Wang, S., Liu, H.H., Gong, H.P., et al. 2012. Chaperone-like effect of the linker on the isolated C-terminal domain of rabbit muscle creatine kinase. Biophys J. 103(3): 558-566. 

Institute of Translational Medicine, Zhejiang University
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