ANYONG XIE, M.B.A., Ph.D.
RESEARCH INTERESTS
1.Studying genomic instability in cancer and developing therapeutics targeting genomic instability;
2.Identifying uniqueness in repair of CRISPR-induced DNA double strand breaks and its applications in CRISPR genome editing;
3.Modeling liver cancers.
PROFESSIONAL EXPERIENCES
Feb 2014-present Professor, Institute of Translational Medicine and Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
Apr 2008-Jan 2014 Instructor, Harvard Medical School, Boston, MA, USA
Apr 2008-Jan 2014 Research Associate, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA
POSTDOCTORAL TRAINING
Sep 2002-Apr 2008 Research Fellow, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA
OTHER PROFESSIONAL EXPERIENCES
Sep 1996-Aug 2002 Research Assistant, Department of Biochemistry, University of Missouri-Columbia, Columbia, MO, USA
Sep 1995-Aug 1996 Research Associate, Institute of Botany, Chinese Academy of Sciences, Beijing, China
Sep 1992-Aug 1995 Research Assistant, Institute of Botany, Chinese Academy of Sciences, Beijing, China
EDUCATION
Sep 1996-Aug 2002 Ph.D. in Biochemistry, University of Missouri-Columbia, School of Medicine, Columbia, MO
Sep 1999-Aug 2001 Master of Business Administration, University of Missouri-Columbia, College of Business, Columbia, MO
Sep 1992-Aug 1995 M. Sc. in Plant Molecular Biology, Institute of Botany, Chinese Academy of Sciences, Beijing, China
Sep 1988-Jul 1992 B. Sc. in Plant Physiology and Plant Biochemistry, Peking University, Beijing, China
EDITORIAL BOARD
2008-present Reviewer, Molecular and Cellular Biology
2013-present Reviewer, Mutation Research
2014-present Reviewer, PLOS Genetics, Nucleic Acids Research, Nature Cell Biology, Nature Medicine, Nature Communications, Oncogene, Acta Biochim Biophys Sin
HORNORS AND AWARDS
2001 Friendship Association of Chinese Students and Scholars (FACSS) Outstanding Service Award, University of Missouri-Columbia
1996 Margaret Cheng Scholarship, University of Missouri-Columbia
1995 President Award of Chinese Academy of Sciences for Outstanding Graduate Student, Chinese Academy of Sciences
1995 Outstanding Research Thesis Award, Institute of Botany, Chinese Academy of Sciences
MEMBERSHIPS
2015- Associate Director of Precision Medicine Group, Medical Society of Zhejiang Province, China
2015- Chinese Society for Cell Biology (CSCB)
2012-Jan 2014 Dana Farber/Harvard Cancer Center Breast Cancer Research Program
PATENT APPLICATION
1. Anyong Xie, Tao Guo, Yili Feng. A novel test system for rapidly predicting CRISPR/Cas9 genomic editing efficiency and its applications. 2016. Chinese Patent Application ID：201610073847.1
FUNDING
2017-2020, Z17C060003, Key Project of Natural Science Foundation of Zhejiang Province, “Roles of ATM in the DSB repair mechanism of CRISPR genome editing”, PI: Anyong Xie;
2017-2020, 31671385, Regular Grant of National Natural Science Foundation of China, “Study of the DSB repair mechanisms in CRISPR genome editing”, PI;
2015-2018, 81472755, Regular Grant of National Natural Science Foundation of China, “Evolution of acquired resistance of PARP inhibitors”, PI;
2016-2018, 2015C03047, Key Project of Department of Science and Technology of Zhejiang Province, “Development of precision medicine in HCC”, PI;
2015-2018, 81472755, Key Project of NSFC–FRQS Research Program on Cancer, “Targeting DDR to develop precision medicine in treating cancer”, Co-PI (PI: Jun Huang)
