Research articles:
1.Feng Y-L*, Liu S-C, Chen R-D, Xie A-Y*. Target binding and residence: a new determinant of DNA double strand break repair pathway choice in CRISPR/Cas9 genome editing. J Zhejiang Univ SCIENCE B 2020; In press
2.Zhang F, Yan P, Yu H, Le H, Li Z, Chen J, Liang X, Wang S, Wei W, Liu L, Zhang Y, Ji X, Xie A, Chen W, Han Z, Pu WT, Chen S, Chen Y, Sun K, Ge B, Zhang B. LARP7 Is a BRCA1 Ubiquitinase Substrate and Regulates Genome Stability and Tumorigenesis. Cell Rep 2020; 32(4): 107974.
3.Kong N, Ji X, Sun X, Chen G, Fan T, Liang W, Zhang H, Xie A*, Farokhzad OC, Tao W*. Mechanistic understanding of the ROS-mediated selective killing of cancer cells by black phosphorus. Nano Letters 2020; 20(5): 3943-3955. (影响因子：12.279)
4.Guo T#, Feng Y-L#, Xiao J-J, Liu Q, Sun X-N, Xiang J-F, Kong N, Liu S-C, Chen G-Q, Wang Y, Dong M-M, Cai Z, Lin H, Cai X-J*, Xie A-Y*. Harnessing accurate non-homologous end joining for efficient precise deletion in CRISPR/Cas9-mediated genome editing. Genome Biol 2018; 19:170. (影响因子：14.028)
5.Xie X, Hu H, Tong X, Li L, Liu X, Chen M, Yuan H, Xie X, Li Q, Zhang Y, Ouyang H, Wei M, Huang J, Liu P, Gan W, Liu Y, Xie A, Kuai X, Chirn GW, Zhou H, Zeng R, Hu R, Qin J, Meng FL, Wei W, Ji H, Gao D*. The mTOR–S6K pathway links growth signalling to DNA damage response by targeting RNF168. Nat Cell Biol 2018; 20: 320-331. (影响因子：17.728)
6.Han J, Ruan C, Huen M, Wang J, Xie A, Fu C, Liu T, Huang J*. BRCA2 antagonizes 53BP1/RIF1/Artemis-dependent classical and alternative nonhomologous end-joining to prevent gross genomic instability. Nat Commun 2017; 8: 1470. (影响因子: 11.878)
7.Feng Y-L, Xiang J-F, Liu S-C, Guo T, Yan G-F, Feng Y, Kong N, Li H-D, Huang Y, Lin H,
Cai X-J*, Xie A-Y*. H2AX facilitates classical non-homologous end joining at the expense of limited nucleotide loss at repair junctions. Nucleic Acids Res, 2017; 45: 10614-10633. (影响因子: 11.147)
8.Guirouilh-Barbat J, Gelot C, Xie A, Dardillac E, Scully R, Lopez BS*. 53BP1 protects against ctip-dependent capture of ectopic chromosomal sequences at the junction of distant double strand breaks. PLOS Genet, 2016; 12:e1006230. (影响因子: 5.224)
9.Tang J-C, Feng Y-L, Guo T, Xie A-Y*, Cai X-J*. Circulating tumor DNA in hepatocellular carcinoma: trends and challenges. Cell Biosci, 2016; 6:32. (影响因子: 3.355)
10.Feng Y-L，Xiang J-F，Kong N，Cai X-J*，Xie A-Y*. Buried territories: heterochromatic response to DNA double strand breaks. Acta Biochim Biophys Sin, 2016; 48:594-602 (受邀综述) (影响因子: 2.502)
11.Chen J, Ji T, Zhao J, Li G, Zhang J, Jin R, Liu J, Liu X, Liang X, Huang D, Xie A, Lin H*, Cang Y*, Cai X*. Sorafenib-resistant hepatocellular carcinoma stratified by phosphorylated ERK activates PD-1 immune checkpoint. Oncotarget, 2016. 7:41274-41284. (影响因子: 5.168)
12.Liu J, Li J, Fu W, Tang J, Feng X, Chen J, Liang Y, Jin R, Xie A, Cai X*. Adenoviral delivery of truncated MMP-8 fused with the hepatocyte growth factor mutant 1K1 ameliorates liver cirrhosis and promotes hepatocyte proliferation. Drug Des Devel Ther，2015; 9:5655-67. (影响因子: 3.208)
13.Liu X-S, Chandramouly G, Rass E, Guan Y, Wang G, Hobbs RM, Rajendran A, Xie A, Shah JV, Davis AJ, Scully R*, Lunardi A*, Pandolfi PP*. LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair. Nat Commun, 2015; 6:8325. (影响因子: 11.878)
14.Liu P, Gan W, Guo C, Xie A, Gao D, Guo J, Zhang J, Willis N, Su A, Asara JM, Scully R, Wei W*. Akt-mediated phosphorylation of XLF impairs non-homologous end joining DNA repair. Mol Cell, 2015；57: 648–661. (影响因子: 14.548)
15.Tang JC, Xie AY, Cai XJ. Diverse functions of fibulin-5 in tumor. Mol Biol, 2014, 48: 761-766. (影响因子: 0.932)
16.Hu Y, Petit SA, Ficarro SB, Toomire KJ, Xie A, Lim E, Cao SA, Park E, Eck MJ, Scully R, Brown M, Marto JA, Livingston DM*. PARP1-driven poly-ADP-ribosylation regulates BRCA1 function in homologous recombination-mediated DNA repair. Cancer Discov, 2014; 4:1430-1447. (影响因子: 26.370)
17.Chandramouly G, Kwok A, Huang B, Willis NA, Xie A, Scully R*. BRCA1 and CtIP suppress long tract gene conversion between sister chromatids. Nat Commun, 2013，4:2404. (影响因子: 11.878)
18.Rass E, Chandramouly G, Zha S, Alt FW, Xie A*. Ataxia telangiectasia mutated (ATM) is dispensable for endonuclease I-SceI-induced homologous recombination in mouse embryonic stem cells. J Biol Chem, 2013，288:7086-7095. (影响因子: 4.106)
19.Scully R* and Xie A. Double strand break repair functions of histone H2AX. Mutat Res，2013，750: 5-14 (peer reviewed). (影响因子: 2.398)
20.Hartlerode AJ, Guan Y, Rajendran A, Ura K, Schotta G, Xie A, Shah JV, Scully R*. Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks. PLoS One, 2012，7:e49211. (影响因子: 2.776)
21.Nguyen CL, Possemato R, Bauerlein EL, Xie A, Scully R, Hahn WC*. Nek4 regulates entry into replicative senescence and the response to DNA-damage in human fibroblasts. Mol Cell Biol, 2012，32: 3963-3977. (影响因子: 3.735)
22.Hu Y, Scully R, Sobhian B, Xie A, Shestokova E, Livingston DM*. RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci. Genes Dev 2011; 25:685-700. (影响因子: 8.990)
23.Xie A, Odate S, Chandramouly G, Scully R*. H2AX post-translational modifications in the ionizing radiation response and homologous recombination. Cell Cycle 2010; 9: 3602-3610. (Highlighted in News and Views in Cell Cycle, 2010; 9:3845). (影响因子: 3.259)
24.Xie A*, Kwok A, Scully R*. Role of mammalian Mre11 in classical and alternative nonhomologous end joining. Nat Struct Mol Biol 2009; 16:814-818 (*, Co-corresponding authorship). (Highlighted in News and Views in Nat Struct Mol Biol 2009; 16:798-800). (影响因子: 12.109)
25.Xie A, Hartlerode A, Stucki M, Odate S, Puget N, Kwok A, Nagaraju G, Yan C, Alt FW, Chen J, Jackson SP, Scully R*. Distinct roles of chromatin-associated factors MDC1 and 53BP1 in mammalian double strand break repair. Mol Cell 2007; 28:1045-1057. (Evaluated and recommended by Faculty of 1000). (影响因子: 14.548)
26.Xie A and Scully R*. Hijacking the DNA damage response to enhance viral replication: γ-Herpesvirus 68 orf36 phosphorylates histone H2AX. Mol Cell 2007; 27:178-179. (影响因子: 14.548)
27.Nagaraju G, Odate S, Xie A, Scully R. Differential regulation of short- and long-tract gene conversion between sister chromatids by Rad51C. Mol Cell Biol 2006; 26:8075-8086. (影响因子: 3.735)
28.Scully R* and Xie A. In my end is my beginning: control of end resection and DSBR pathway “choice” by cyclin-dependent kinases. Oncogene 2005; 24:2871-2876. (影响因子: 6.634)
29.Xie A, Puget N, Shim I, Odate S, Jarzyna I, Bassing CH, Alt FW, Scully R*. Control of sister chromatid recombination by histone H2AX. Mol Cell 2004; 16:1017-1025. (影响因子: 14.548)
30.Scully R* and Xie A. BRCA1 and BRCA2 in breast cancer predisposition and recombination control. J Mammary Gland Biol Neoplasia 2004; 9:237-246. (影响因子: 2.758)
31.Scully R*, Xie A, Nagaraju G.Molecular functions of BRCA1 in the DNA damage response. Cancer Biol Ther 2004; 3:521-527. (影响因子: 2.879)
32.Xie A-Y and Folk WR*. Inhibition of polyomavirus ori-dependent DNA replication by mSin3B. J Virol 2002; 76:11809-11818. (影响因子: 4.324)
33.Xie A-Y, Bermudez VP, Folk WR*. Stimulation of DNA replication from the polyomavirus origin by PCAF and GCN5 acetyltransferases: Acetylation of large T antigen. Mol Cell Biol 2002; 22:7907-7918. (影响因子: 3.735)
34.Berjanskii MV, Riley MI, Xie A, Semenchenko V, Folk WR, Van Doren, SR*. NMR structure of the N-terminal J domain of murine polyomavirus T antigens. Implications for DnaJ-like domains and for mutations of T antigens. J Biol Chem 2000; 275:36094-36103. (影响因子: 4.106)
35.Yong W-D, Liang T-B, Xie A-Y, Li C, Song Y-R*. PhbB, phbC gene expression in E. coli and their transformation and identification in potato. Acta Botanica Sinica 1998; 40:615-621. (影响因子: 0.599)
36.Xie A-Y, Cui X-J, Song Y-R*. Cloning and sequencing of Alcaligenes eutrophus H16 phbB and phbC genes and construction of their plant expression vectors. Acta Botanica Sinica 1995; 37:581-588.
37.Song Y-R* and Xie A-Y. Biosynthesis of ethylene and molecular regulation of fruit maturation. Acta Botanica Sinica 1994; 36 (SUPPL.):1-13.
38.Xie A-Y and Song Y-R*. Applications of biotechnology in producing biodegradable plastic PHB. Chinese Bulletin of Botany 1994; 11:21-25.
